three cause unpleasant side effects that get worse once you pass 60 especially back and leg pain. The side effects are dosage related. Cialis stays in your system for a couple of days and kicks in within 20 minutes of taking. But it has the strongest negative side effects especially back and leg
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pain. Viagra is the least effective of all three major ED drugs with the usual side effects. Takes a long time to kick in leaves your body within a couple of hours. Beware OTC meds that contribute to ED antacids antihistamines some NSAIDs and melatonin. And even one glass of wine or a full stomach can worsen ED so I like to have sex in the morning or before
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