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What is the half life of anastrozole? Elimination of anastrozole is primarily via hepatic metabolism (approximately 85%) and to a lesser extent, renal excretion (approximately 11%), and anastrozole has a mean terminal elimination half - life of approximately 50 hours in postmenopausal women.
How long does Aromasin stay in your system? Exemestane is distributed extensively into tissue. At a dose of 25mg, maximal estrogen suppression occurs by 2 to 3 days. With daily repeated administration, steady state is reached within 7 days. Exemestane is extensively (90%) metabolized in the liver by cytochrome P450 isoenzyme 3A4 and aldoketoreductases.
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