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What SSRI has the least side effects? They rated SSRIs at least as helpful as SNRIs but with fewer side effects. Note that bupropion (Wellbutrin and generic) has approval only for treating depression, not anxiety. Readers rate antidepressants. Drug class SSRIs (Celexa, Lexapro, Prozac, Zoloft) Side affects Weight gain 16% Dry mouth 13% Sleep problems 12% 2 more columns Dexter Fewings search endep

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