increase in e-cigarette use by U.S. high school students, and 3.6 million high school and middle school students now use e-cigarettes, according

marketing have had little effect, NBC News reported. "I'll tell you this. If the youth use continues to rise, and we see significant increases in use in 2019, on top of the dramatic rise in
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2018, the entire category will face an existential threat," he said Friday. "It will be game over for these products until they can successfully
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traverse the regulatory process," Gottlieb warned. The FDA has the authority to block e-cigarette sales and force makers to go through the formal FDA approval process, but has not done so to this point. There has been a 78 percent
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