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Is Paget's disease inherited? Some people have hereditary Paget's disease, which means it runs in their family and was passed down by their parents. But most people do not have any relatives with Paget's disease. Doctors think a virus may cause Paget's disease in some cases.
What are the dangers of Prolia? Two years after its approval, Amgen issued warnings that Prolia could cause serious risks like "hypocalcemia, serious infections, suppression of bone turnover, including osteonecrosis of the jaw" as well as "atypical femoral fracture" and "dermatologic adverse events." Notably, these are the same risks bisphosphonates
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