have had little effect, NBC News reported. "I'll tell you this. If the youth use continues to rise, and we see significant increases in use
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in 2019, on top of the dramatic rise in 2018, the entire category will face an existential threat," he said Friday.
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"It will be game over for these products until they can successfully traverse the regulatory process," Gottlieb warned. The FDA has the authority to block e-cigarette sales and force makers to go through the formal FDA approval process, but has not done so to this point. There has been a 78 percent increase in e-cigarette use by U.S. high school students,
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