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What is the active ingredient in allopurinol? ZYLOPRIM (allopurinol) is known chemically as 1,5-dihydro-4H-pyrazolo [3,4-d]pyrimidin-4-one. It is a xanthine oxidase inhibitor which is administered orally. Each scored white tablet contains 100 mg allopurinol and the inactive ingredients lactose, magnesium stearate, potato starch, and povidone.
Is allopurinol hard on the kidneys? Allopurinol Safe Even With Chronic Kidney Disease. Allopurinol is a safe and effective therapy for lowering urate levels in gout, even in patients with creatinine clearances (CrCL) < 30 mL/min. High doses of allopurinol are rarely needed to achieve acceptable urate levels in patients with chronic kidney disease.
